Monolith Basics

Fluid Transport

Dry monolith material self wicks. On contact, fluid is pulled spontaneously through the porous monolith scaffold. This eliminates the requirement for centrifugation, vacuum or liquid handling equipment to enable unpowered sample processing applications.

In wet monolith, liquids can be moved through the material pores using gentle vacuum or low g-force centrifugation.

Chemical Modification

Monolith chemistry can be customized to perform multiple sequential process steps. This reduces per-sample labor costs and mitigates the risk of human error.

The fundamental monolith formulations are bio-inert, and can be configured to perform a variety of filtration operations. In addition, monolith can be modified to perform ion-exchange, DNA hybridization, fluorescent probe immobilization and even enzymatic reactions.

Form Factors

The monolith (matrix) modules can be formed in a wide variety of geometries. With sample capacity ranging from 10 uL to 10 mL, it is well suited to device interface or stand-alone applications.